Internal Medicine Essentials
American College of Physicians



Cardiovascular Medicine

Page 5: Approach to Chest Pain, Pulmonary Causes: The fifth sentence should read "A negative D-dimer, a test for PE with a high sensitivity but low specificity..." instead of "with high specificity but low sensitivity." (Added November 2017)

Page 18: Supraventricular Arrhythmias, Introduction: The second sentence should read "Because supraventricular impulses below the AV node are conducted normally, the electrocardiogram (ECG) in SVT usually reveals a narrow complex tachycardia, although the QRS complexes can be wide (>120 msec) in the presence of bundle branch block, aberrancy, pacing, or anterograde accessory pathway conduction (eg, antidromic tachycardia)." (Added April 2016)

Page 38: Vascular Disease, Aortic Disease, Aortic Dissection, Follow-Up: The last sentence should read "...recurrence or extension of the dissection," rather than "of the aneurysm." (Added April 2016)

Endocrinology and Metabolism

Page 47: Hypothalamic and Pituitary Disorders, Anterior Pituitary Diseases, Hormone Overproduction, TSH-Secreting Tumors: In the second sentence, "hyperthyroidism" should appear, instead of "hypothyroidism." (Added December 2015)

Page 51: Thyroid Disease, Therapy, Hypothyroidism: The fifth sentence of the stem should read "This recommendation excludes women seeking pregnancy or currently pregnant, who should be treated once TSH rises above 2.5 μU/mL (2.5 mU/L)," rather than 2.5 IU/L. (Added October 2016)

Gastroenterology and Hepatology

Page 89: Hepatitis, Screening: The second sentence should read "The United States Preventive Services Task Force has recommended that all persons at high risk for infection be screened for hepatitis C, as well as a one-time screening for all adults born between 1945 and 1965." (Added April 2016)


Page 214: Hematopoietic Stem Cell Disorders, Myeloproliferative Neoplasms, Essential Thrombocythemia: In the first sentence, "Essential thrombocythemia" should appear, instead of "Essential thrombocytopenia." (Added December 2015)

Infectious Disease

Page 234: High Value Care Recommendations: The last bullet should read "A follow-up urinalysis or culture is not indicated after treatment for an uncomplicated urinary tract infection with symptom resolution." (Added November 2017)

Page 241: Community-Acquired Pneumonia, Prevention: In the second sentence, "the specific seasonal vaccine prepared for that year" should appear, instead of "the 23-valent pneumococcal polysaccharide vaccine (PPSV23)." (Added December 2015)

Page 267: Sepsis Syndrome, Table 1. Definition of Systemic Inflammatory Response Syndrome: In the second row, the first value should be 38.0°C, instead of 38.3°C. The row should read "Temperature >38.0°C (100.4°F) or <36.0°C (96.8°F)." (Added December 2015)


Page 282: Fluid and Electrolyte Disorders, Hyponatremia: In the second sentence, "hyperosmolal hyponatremia" should appear in parentheses, instead of "hyperosmolal hypernatremia." (Added September 2015)


Page 434: Infectious Arthritis, Therapy: In the third paragraph, fifth sentence, "...a third-generation cephalosporin with activity against Pseudomonas (such as cefotaxime) with an aminoglycoside...," the drug in parentheses should be "ceftazidime," instead of "cefotaxime." (Added September 2015)

Page 435: Rheumatoid Arthritis, Table 1. The 2010 ACR/EULAR Classification Criteria for Rheumatoid Arthritis: In the second row under category "A. Joint involvement (swollen or tender)," "2-10 large joints" should appear, instead of "2-10 small joints." (Added December 2015)


General Internal Medicine

Page 105: General Internal Medicine, Item 53: The last sentence of the stem should read "After estrogen priming followed by a progesterone challenge, bleeding occurs." (Added October 2016)

Page 117: Item 10: In the second paragraph, the last sentence should read "...(or at least 6 to 12 months later after receiving PCV13)." (Added November 2017)


Page 160: Hematology, Item 1: The fifth sentence of the first paragraph should read "In contrast, iron deficiency is associated with decreased transferrin saturation, increased calculated serum TIBC levels, and decreased serum ferritin levels." (Added April 2016)

Page 162: Hematology, Item 7: The first sentence of the second paragraph should read "temperature less than 38.3°C (100.9°F)," instead of "temperature greater than 38.5°C (101.3°F)." (Added April 2016)

Page 163: Hematology, Item 9: The second sentence of the first paragraph should read "temperature less than 38.3°C (100.9°F)," instead of "temperature less than 38.5°C (101.3°F)." The first sentence of the third paragraph should read "Furosemide may be helpful in patients who have hypervolemia," instead of "hypovolemia." (Added April 2016)


Page 235: Neurology, Item 22: In the first sentence of the second paragraph, "palmar flexion" should appear, instead of "plantar flexion." (Added December 2015)

Page 243: Neurology, Item 12: The second paragraph should read "The evidence for using the combination of aspirin and clopidogrel for stroke prevention is mixed, and it is not routinely given in this circumstance. Trials are underway to clarify the use of dual antiplatelet therapy in patients with acute stroke." (Added April 2016)


Page 314: Rheumatology, Item 28: In the last sentence of the second paragraph of the critique, the phrase "However, there is no clear relationship to IBD" was deleted. The sentence should read "This patient's lack of cutaneous findings makes psoriatic arthritis unlikely." (Added October 2016)